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If a patient is unresponsive to steroid treatment, the current guidelines recommend escalating therapy by combining immunosuppressive drugs such as calcineurin inhibitors (Cyclosporin, Tacrolimus), mycophenolate mofetil, anti-CD20 monoclonal antibodies (Rituximab, Ofatumumab), and CTLA- 4 (Abatacept, Belatacept)

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Meanwhile, kimchi supplements mirror continued focus on gut health, as more consumers look for probiotic-rich alternatives inspired by fermented foods to support digestion and microbiome balance